£20m funding competition for blood and transplant research

The NIHR has partnered with NHS Blood and Transplant (NHS BT) to announce a funding competition to award £19.9 million to new NIHR Blood and Transplant Research Units (BTRUs).

NIHR currently funds four NIHR BTRUs, which are centres of multidisciplinary research excellence in human translational medicine related to blood and organ transplantation. The units, partnerships between universities and NHSBT, undertake research to improve the supply of blood, blood products, stem cells, tissues, and organs for transplantation. 

The current BTRUs have developed many scientific advances and benefits to patients, for example they have developed a new approach to protect donated livers for transplantation, so that more can be used for patients with liver disease, and created a technique to produce red blood cells in the lab

Another BTRU project has informed a change in how blood donors are screened for haemoglobin status, increasing the efficiency of blood donation sessions nationwide. A fourth project is developing automated manufacturing for ground-breaking CAR T-cell therapy for patients with leukaemia. The current BTRUs are due to come to an end in March 2022. 

The new funding competition is seeking to fund new BTRUs that will focus on the following priority areas: blood donation; organ donation and transplantation; therapeutics; data driven transfusion practice; and transfusion and transplantation transmitted infections. Five BTRUs will be funded for a five year period, one in each area. 

Dr. Louise Wood CBE, director of science, research and evidence at the Department of Health and Social Care and co-lead for the NIHR, said: “Since 2014 NIHR’s investment in blood and organ transplantation research has translated new findings into benefits for people who are donating, or receiving, blood or organs. Through this new funding competition, we will continue to support an environment where world-class research on blood and organ transplantation can thrive.”

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