Sugar given to newborn babies as a routine form of pain relief does not work, according to a new study led by UCL researchers and published in The Lancet. Instead, sucrose changes the facial expressions of some babies giving the impression that pain is being relieved.
The finding could lead to future changes in healthcare policy as oral sucrose is frequently given to relieve procedural pain in newborn babies who must undergo invasive procedures, such as taking blood from a vein or heel lances. The trial, funded by the Medical Research Council, studied 59 newborn, healthy babies at University College Hospital and found that activity in the pain areas of the brain did not differ regardless of whether they were given sucrose for pain relief. There was little difference between the infants’ leg reflex reactions either, which also indicates discomfort. Scientists measured pain activity in the brain and spinal cord before and after babies had undergone a routine heel lance – a standard procedure used to collect blood samples from babies. Half the babies were given a sucrose solution prior to the lance, as per the standard procedure, and the remainder were given sterilised water. Brain activity was measured using neonatal electroencephalography (EEG) and spinal cord pain reflex was recorded with electromyography (EMG).