Government invests £375m in neurodegenerative disease research

People living with neurodegenerative diseases could live longer, healthier lives due to innovative new research, following a government commitment to invest £375 million over the next 5 years.

At least £50 million will be made available specifically for research to help find a cure for MND – a condition that affects the brain and nerves and affects 5,000 people in the UK. New, innovative projects will help researchers to better understand the disease and its related conditions, develop and test treatments and improve care for those living with MND.

The full £375 million investment will fund projects into a range of diseases such as Pick’s Disease, Fronto-temporal dementia, wernicke-korsakoff, Parkinson’s disease dementia, Lewy Body dementia, Alzheimer’s disease and mild cognitive impairment, improving understanding while searching for new treatments.

For MND, a new NIHR research unit will be set up to co-ordinate research applications for the new funding, encouraging more innovative studies with the ultimate goal of finding a cure.

The government has already invested millions of pounds in MND research, including over £7 million to support pioneering clinical trials, which have led to major advances in how the disease is understood. This includes improving our understanding of how different types of MND are passed on genetically which could unlock new treatment options for patients using gene therapy.

There is currently only one drug licensed in the UK to treat MND – Riluzole – which slows the progression of the disease and extends someone’s life by a few months. The funding announced will accelerate progress across the UK to find better treatments for MND, and give people living with the condition the chance of a better quality of life, and more good years with their loved ones.

The NIHR has committed to ongoing research into MND, reinforced by issuing a Highlight Notice inviting applications from ambitious research projects to take potential treatments from the lab to the clinic, as part of scaled-up efforts to significantly improve the care and support available.

The NIHR has also awarded a prestigious Research Professorship to leading MND researcher Professor Chris McDermott. The award will focus on improving care for people with MND, bolstering leadership in this area of research, and strengthening the design of clinical trials to help more people with the disease take part.

As well as the funding for research into neurodegenerative diseases, a new MND partnership will be formed to pool expertise and resources across the research community to accelerate the delivery of new treatments. Researchers can apply for funding via the NIHR and UKRI websites.​

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