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Imperial vaccine lead says COVID is here for years to come

Imperial’s COVID-19 vaccine lead, Professor Robin Shattock, has told MPs that there is uncertainty around the immunity that a vaccine will offer; boosting strategies may be required and we are likely to be living with the virus for years to come.

Professor Shattock, speaking to the Science and Technology Committee, said that a vaccine would make life much better and reduce fatalities but we are still likely to be living with the virus for the next few years. Professor Shattock, from the Department of Infectious Disease, also updated MPs on the progress of Imperial's vaccine.

Professor Shattock said: "Right now we don’t know which, if any, of these vaccines will work, and what success will look like, whether that’s success at preventing disease or preventing transmission.

"One of the advantages of the technology we are developing is it can be used for repeated boosting immunisations, either to boost existing vaccines or itself. If immunity wanes, we would be well positioned with this technology to provide boosting strategies for the UK.

"Until we get information about whether any of the vaccines block transmission, the question about rolling out widely in UK population remains unanswered."

He added: "It’s certainly possible the first vaccines may reach the bar of preventing severe disease but may not necessarily block transmission. They may be introduced first but as we see later vaccines that may be more potent, we may see they are replaced.

"It's quite likely we will have a number of vaccines introduced and we won't know how long they provide immunity for, so we certainly need to have a strategy for re-boosting. The approach we are developing is particularly suitable for re-boosting campaigns because you get no immunity against the vaccine itself which can occur in some other vaccines."

Traditional vaccines are often based on a weakened form of a virus or parts of it, but the Imperial vaccine is based on a new method. Instead, it uses bits of genetic code (called self-amplifying RNA), rather than bits of the virus. Once injected into muscle, the cells should produce copies of a protein found on the outside of the virus. This trains the immune system to respond to the coronavirus so the body can easily recognise it as a threat in future.

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Upcoming Events

AfPP Annual Conference 2022

University of York
8-11 September 2022

Infection 360: What's trending in infection prevention & control

Edgbaston Stadium, Birmingham
27-28 September 2022

IP2022 IS COMING TO BOURNEMOUTH IN OCTOBER 2022

Bournemouth
17-19 October 2022

UKHCA Conference: Listen Up

Pendulum Hotel and Manchester Conference Centre, Manchester
3rd November 2022

MEDICA 2022

Dusseldorf Germany
14th November - 17th November

Future Surgery 2022

ExCel, London
15th - 16th November 2022

Access the latest issue of Clinical Services Journal on your mobile device together with an archive of back issues.

Download the FREE Clinical Services Journal app from your device's App store

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