NICE has published final guidance recommending the use of prasugrel in combination with aspirin as an option for preventing blood clots in the arteries of people with acute coronary syndromes.
The guidance recommends prasugrel in combination with aspirin as an option for individuals who are having percutaneous coronary intervention, only when immediate primary percutaneous coronary intervention for ST-segmentelevation myocardial infarction (a specific type of heart attack) is necessary; or a blood clot blocking a stent has occurred during treatment with clopidogrel; or the patient has diabetes mellitus. People currently receiving prasugrel for treatment of acute coronary syndromes whose circumstances do not meet these criteria should have the option to continue therapy until they and their clinicians consider it appropriate to stop.