Tens of thousands of people with Jewish ancestry who are more likely to carry a genetic fault that can increase the risk of developing some cancers will receive genetic testing through a new programme announced by the NHS in England.
With plans to identify thousands more people carrying faults in the BRCA genes over the next 2 years so they can seek early access to surveillance and prevention services, the testing programme is part of the NHS’s major drive to catch tumours early when they are easier to treat.
BRCA refers to 2 genes, BRCA1 and BRCA2, which repair DNA damage and normally help to protect against cancer. Some individuals are born with a fault in one of these genes, and this increases their likelihood of developing certain cancers, including breast, ovarian, prostate and pancreatic cancer.
People with Jewish ancestry are around 6 times more likely to carry such genetic faults than the general population. The new national NHS Jewish BRCA Testing Programme will see anyone over the age of 18 with Jewish ancestry offered a simple genetic saliva test to look for the presence of BRCA1 or BRCA2 faults.
The saliva samples will be carried out at home and then be sent to labs for testing. During the pilot phase of the programme, thousands of people have already come forward for testing and the national roll-out will see around 30,000 people tested over the next 2 years.
People with at least one Jewish grandparent can register for a saliva kit to be sent to their home address by visiting: https://jewishbrca.org/
Charities Jnetics and Chai Cancer Care have been running an engagement campaign to help raise awareness in Jewish communities and encourage a significant number of men and women with Jewish ancestry to come forward for a free test.
Peter Johnson, National Clinical Director for Cancer at NHS England said: “BRCA testing for the people most at risk has the potential to save lives, by allowing them to take steps to reduce the chance of cancers developing or making sure that any cancer can be detected as early as possible, with those at increased risk able to take advantage of surveillance and prevention programmes with their health teams."