Research demonstrates photodisinfection efficacy against extensively drug-resistant bacteria

Ondine Biomedical has presented new research at the 2023 International Consortium on Prevention & Infection Control (ICPIC) in Geneva, demonstrating high efficacy of its patented photodisinfection technology against extensively drug-resistant (XDR) bacteria.

The study demonstrates that Ondine’s Steriwave photodisinfection technology is highly effective (>99.99% kills in 20 seconds) against both moderately drug-resistant (MDR) and extensively drug-resistant (XDR) pathogens. Gram-negative bacteria, such as Escherichia coli, Pseudomonas aeruginosa, Enterobacter cloacae, and Klebsiella pneumoniae cause many serious healthcare-associated infections.  The research underlines the potential for Steriwave to become a rapid, broad-spectrum, bactericidal alternative to antibiotics.

Antimicrobial resistance (AMR) poses an urgent global public health threat resulting in 1.27 million annual deaths worldwide, and is predicted to become one of the largest threats to human health in the coming years. The emergence and worldwide spread of extensively drug-resistant (XDR) microbes is highly concerning, as infections caused by these pathogens are virtually untreatable because they are proving resistant to almost all approved antimicrobial agents.

Dr. Nicolas Loebel, Ondine’s CTO and President, commented: “Overuse of antibiotics over decades has caused adaptation in many microbes, and we now see multidrug resistance (MDR) evolving into extensive drug resistance (XDR) in bacteria, rendering even the most powerful combination of drugs ineffective. We believe photodisinfection can play a significant role in cost-effectively combatting these drug-resistant pathogens and reducing global reliance on antibiotics.”

The poster presentation, “Antimicrobial Photodynamic Therapy Against Extensively Drug-Resistant (XDR) Gram-Negative Isolates With Novel Antibiotic Resistance Factors”, was presented at the 7th International Consortium on Prevention & Infection Control (ICPIC). ICPIC is a leading international conference on the prevention of healthcare-associated infections and the control of antimicrobial resistance around the world.

Latest Issues

AfPP Annual Conference 2024

University of Warwick
2nd - 3rd August 2024

The Operating Theatres North Show 2024

Etihad Stadium, Manchester
12th September 2024

The AfPP Roadshow - London

Cavendish Conference Centre, London
14th September 2024

Infection Prevention 2024

ICC Birmingham
23rd - 25th September 2024

The AfPP Roadshow - Glasgow

TBA, Glasgow
5th October 2024

CSC Autumn Study Day 2024

Crowne Plaza Birmingham NEC
14th October 2024