Blood plasma treatment has limited effect for sickest COVID patients

Treating critically ill COVID-19 patients with blood plasma from people who have fought off the disease has limited impact on patient outcomes.

The early findings, which are yet to be published, come from the REMAP-CAP study and show that treatment with convalescent plasma did not improve outcomes among patients requiring intensive care unit (ICU) support.

There was no evidence of harm associated with the administration of convalescent plasma, but investigators have paused enrollment of severely ill COVID-19 patients in ICU to this arm of REMAP-CAP study.

They explain the trial will continue to recruit hospitalised COVID-19 patients who are moderately unwell and are not requiring intensive care, to assess if less severely ill patients benefit from the treatment.

Professor Anthony Gordon, professor of anaesthesia and critical care at Imperial College London and an NIHR research professor, said: “I am glad REMAP-CAP has been able to provide important evidence about which patients might benefit from convalescent plasma.

“Although it is disappointing that all critically ill patients don’t appear to gain any benefit, this is still vitally important to know. Convalescent plasma is a precious resource, and we can now continue to focus on identifying exactly which patients might benefit the most from treatment – maybe people earlier in their illness or those with weak immune systems.”

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Upcoming Events

Managing Deteriorating Conditions 2021

National Conference Centre Birmingham
19th April

Infection Prevention & Control Conference 2021

National Conference Centre Birmingham
20th - 21st April

BSG Annual Meeting 2021

SEC Glasgow, Glasgow, G3 8YW
19th - 21st May

EBME Expo 2021

Marshall Arena, Stadium MK, Milton Keynes Stadium Way West Milton Keynes MK1 1ST
30th June - 1st July

Central Sterilising Club 60th Anniversary Annual Scientific Meeting

Crowne Plaza, Bridge Foot, Stratford-upon-Avon, CV37 6YR
4th - 5th April