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So You Think You Know About The Risks From Formalin Spills?

Formaldehyde is a colourless, corrosive gas, which has a pungent, irritating odour. When used at 5% solution with water as a disinfectant as it is effective in killing bacteria, fungi and viruses. Formalin, the most commonly used form of formaldehyde in healthcare, is the standard fixative for histological specimens. It is a solution of approximately 4% formaldehyde and water (known as 10% NBF) and is ubiquitous in clinical laboratories, pathology laboratories, and in operating rooms.

 
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Despite Fischer’s 1905 publication demonstrating the adverse effects of formaldehyde and formalin2, it is only in recent years that both the International Agency for Research on Cancer (IARC)3 and the European Union4 have classified formaldehyde as a Class 1B carcinogen and Class 2 mutagen.  

Other adverse effects, noted in Fischer’s paper,2 arise from exposure to formalin and formaldehyde such as  irritation of the nose, throat and mouth if inhaled, burns and ulcers in the stomach or intestines if ingested, burns from vapour,  redness, itching, rash and swelling of the skin from formaldehyde contact, and irritation, stinging, burning, tearing and eyelid spasms in eye contamination.1

Issues

In addition to the guidelines produced by the Control of Substances Hazardous to Human Health (COSHH) (Health and Safety Executive (HES)5 relating to the handling of hazardous substances, most healthcare organisations have local guidance on the collection, labelling and transport of specimens. These include:

  • Identifying the correct size of container for the specimen
  • Filling of the container with formalin
  • Wearing of protective clothing
  • Storing of specimen containers for collection

 

However, during biopsy procedure in the operating room, surgeons and nurses are always exposed to a certain level of risk; for example, formalin may accidentally spill on the skin, or its vapours might affect the respiratory system & the eyes when they handle biopsies with the traditional pre-filled containers. A study by Steeleman et al6, found that of 648 adverse events, an incorrect collection technique occurred in 3.5% of cases (n=23), which could lead to accidental exposure.

In addition to those problems, modern healthcare institutions often have multiple clinics, hospitals, operating rooms, and laboratories at separate geographic locations. This requires that surgical tissue samples be transported over significant distances in formalin-filled containers, greatly increasing the risk of spills.

Spill management

Being such a light and highly volatile molecule, formaldehyde has a tendency to evaporate very easily, whenever a spillage or a leakage occurs. Standard procedure in most hospital or laboratory environments would include cordoning off the spill area during clean-up, and potentially evacuating personnel to avoid exposure to fumes. However, ordinary formaldehyde neutralizers need a long time to take effect and there is a lack of solutions against ordinary formalin contamination

Public Health England guidance recommends wet decontamination and removal of clothing for formaldehyde/formaldehyde solutions exposure, with spills to be managed using an appropriate decontamination kit.7

 

Weakness of current spill management solutions

It is not enough to be equipped with an emergency response kit solely for the management of large formalin spillages since much smaller scale spillages can occur daily. Ordinary clean-up procedures cannot completely remove the residual formalin as the surface will remain contaminated and continue to release formaldehyde gas into the environment. Even if the amount is not appreciable, it is still considered a safety concern. Furthermore, current response solutions take much longer to act on any residual formalin, leading to further safety concerns for staff who are required to deal with smaller spillages.

Any system that would minimize or eliminate the amount of fixative/formalin would be desirable.

 

The Complete Formalin Safety Solution for Hospital Pathology and Theatre Departments

Novok® is a patented (Patent No. 102018000002334) solution that can quickly decompose formaldehyde molecules on contact, without leaving any residual behind. It allows healthcare staff to perform a deep decontamination inside their workplace whenever necessary, and can be used as in the daily cleaning procedures promote a healthier work environment and minimum exposure to the hazardous substance.

 

The Novokit contains both the Novok-S® + Novok-Pow® sets, all the necessary cleaning material and personal protective equipment (PPE), minimising exposure to carcinogenic vapours during the spill management procedure.

 

Novok-Pow is a highly absorbent polymeric powder which, when applied to a formalin spill, rapidly inflates and solidifies the liquid mass. Novok-S is a liquid spray which has a high oxidizing power on formaldehyde particles. When Novok-S is sprayed on to the solid mass of Novok-Pow, they work in conjunction to rapidly eliminate formaldehyde particles in the environment and facilitate a quick and safe clean-up process.

 

Both Novok-S and Novok-Pow on their own can easily manage smaller spills up to 60ml without the need for any additional safety equipment. However, for any larger spillages, we recommend a full spill kit with additional safety equipment to protect staff from exposure to formalin during the clean-up process. We also supply the Novokit which contains enough Novok-S & Novok-POW to deal with spillages all the way up to six litres.

The contents of the Novokit include: 

  • 500ml anti-formalin solution: novok-s®
  • 400g Formalin thickener: novok-pow®
  • A pair of nitrile gloves
  • Vented goggles
  • Scoop & scraper
  • Respirator with filters against formaldehyde
  • Absorbent pad
  • Disposable open back gown
  • Biohazard bag
  • Shoe covers
  • “Caution” sign
  • Instruction sheet

Conclusion

The use of these substances carries an inherent risk of exposure, so to protect users, an effective, efficient and safe method of dealing with exposure is vital. The Novokit can provide such assurance.

 
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Upcoming Events

Central Sterilising Club - Annual Scientific Meeting 2024

Crowne Plaza at Gerrard’s Cross
15th April 2024 – 16th April 2024

DECON UK 2024

National Conference Centre, Birmingham
17th April 2024

Infection Prevention & Control

National Conference Centre, Birmingham
23rd - 24th April 2024

Theatres & Decontamination Conference 2024

Coventry Building Society Arena
16th May 2024

The AfPP Roadshow - Birmingham

Millennium Point, Birmingham
18th May 2024

The AfPP Roadshow - Exeter

University of Exeter
22nd June 2024

Access the latest issue of Clinical Services Journal on your mobile device together with an archive of back issues.

Download the FREE Clinical Services Journal app from your device's App store

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