Standards and controls for skin disinfection

DR TIM SANDLE considers best practice in the use of chlorhexidine skin disinfection, prior to surgery, with the aim of reducing the risk of surgical site infection.

The application of a cutaneous solution for disinfection of the intact skin is part of good surgical practice prior to any invasive procedures taking place. This includes pre-operative skin disinfection. Disinfection is undertaken through the use of a skin disinfectant (commonly termed an antiseptic).1 Antiseptics can be classified as bactericidal (capable of killing most members of a population of microorganisms) or bacteriostatic (capable to inhibiting the growth of members of a population of microorganisms). In general, bactericidal products are preferred. 

The correct application of a suitable antiseptic is necessary to minimise the risk of surgical site infection. This class of infection accounts for about 15% of all healthcare-associated infections in total and about 37% of the hospital-acquired infections of surgical patients.2, 3 

The ideal antiseptic agent should be effective against a wide range of microorganisms; work within a fast onset of action; exert a long-term effect; and not be readily inactivated by organic material (e.g. blood). Moreover, it should have minimal toxic effects on the skin. For pre-operative surgery, the most commonly used antiseptic is the skin disinfectant chlorhexidine. Chlorhexidine is well-established in the clinical field. It was discovered in 1946 and introduced into clinical practice in 1954. Today, chlorhexidine is probably the most widely used antiseptic in the world.4

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